摘要
用皮温测定、激光多普勒,墨汁灌注,微血管造影及透明标本等方法对大鼠真皮下血管网皮瓣与传统皮瓣带蒂移植后血运重建作了对比研究。结果表明,一定长宽比例的鼠真皮下血管网皮瓣早期可以藉蒂部供血成活,术后24小时开始微循环重建.术后5天皮瓣可以断蒂而依赖重建血供成活;对照组移植后全部成活,术后3天才开始微循环重建,第5天断蒂,皮瓣均有不同程度的坏死.
A comparative study of skin flap with a preserved subcutaneous vascular network and conventional skin flap was uadertaken in rats with determination of skin temperature, laser Doppler,ink perfusion,microangiography and transparent specimen technics.It was found that all the skin flaps with a preserved subcutaneous vascular network survived aft- er transplantation.Three hours postoparation,the flap microcirculation was poorest(LDF, 28% of the preoperative value).Six hours postoperation,it began to augment,and micro- vessels containing ink could be seen under microscope at 24 hours,as compared to 3 days postoperation in the controls.On the fifth day.LDF returned to the preoperative level, and the diameter and density of reformed miecovessels were similar to the vessels of the adjacent skin.This phenomenon only occurred on the 7th day in the controls.After divis- ion of the pedicle on the fifth day,all the flaps survived,while the controls showed par- ial necrosis.The results indicate that skin flaps with a preserved subcutaneous vascular network can survive on the blood flow of pedicle in the early staze,at 24 hours postopera- tion flap mierovessels begin to reform,and on the fifth day flaps can survive on the reformed microcircalation in spite of the severance of the podicle.
