中国成都汉族群体三个Y-STR基因座复合扩增及其单倍型的研究

A population study of three Y-STR loci by multiple xing in Han population in Chengdu,China

目的建立一种同步检测Y-STR基因座的方法。方法采用复合扩增的方法同时对三个基因座(DYS390、DYS391及DYS393)进行扩增。结果成功地对这三个Y-STR基因座进行了同步扩增,并用其对中国成都汉族群体进行群体遗传学研究。结论三个Y-STR基因座在中国成都汉族群体个人识别几率为0.8965±0.0081,证明这个体系可用于个人识别和群体遗传学研究。

Objective To establish a better met ho d determing three Y-STR loci.Methods A multiplex of Y-STRs and amplify simultane ously three Y-STRs loci.Results Establish successfully a multiplexing sys - tem of three Y-STR loci(DYS390,DYS391and DYS393)followed by a population gen etic study of Han population in Chengdu,China.Conculusion The diversity of haplo type is0.8965,the value of discrimina - tion and the chance of exclusion chance is0.8965with the standard error0.008 1.This established system is one of the good tools in personnal identification a nd genetic study.[