慢支急发期痰热壅肺证、痰浊阻肺证患者的呼吸道微生态研究

Respiratory Micro-ecological Study on the Acute Stage of Chronic Bronchitis of Lung Phlegm-Heat Syndrome and Lung Phlegm-Turbidity Syndrome

为研究慢性支气管炎急发期痰热壅肺证、痰浊阻肺证患者的咽部微生态状况 ,探索中医辨证分型与微生态量化指标的内在联系。筛选出 15 2例符合慢性支气管炎急性发作期痰热壅肺型、痰浊阻肺型患者 ,进行呼吸道微生态检测。结果 :两型患者菌群密集度增多 ,多样性降低 ,优势菌改变 ,痰浊型患者较痰热型患者变化更为显著。慢支急发期痰热壅肺型、痰浊阻肺型患者的咽部微生态明显失衡。提示两型之间的微生态指标差异可初步从微生态角度揭示中医证型的科学性 ,为中西医结合防治本病提供新的思路。

To study the micro-ecological condition in the throat of the acute stage of chronic bronchitis of phlegm heat and phlegm turbidity in lungs, this paper discusses the intrinsic relation between Chinese medical syndrome and micro-ecological indexes in 152 cases. Results: In both syndromes, the flora density increased, variety reduced and dominant bacteria improved, with more significant changes in phlegm heat syndrome than in phlegm turbidity syndrome; there was a marked micro-ecological imbalance in these subjects. It is indicated that micro-ecological difference can provide scientific evidence for Chinese medical syndrome differentiation.