摘要
以清洁级ICR小鼠为实验动物,研究化工厂废水中非挥发性物质对小鼠的生殖毒性.采集化工厂的生产用水、未处理的生产废水、已处理的生产废水各70L,经浓缩吸附后对成年的雄性小鼠腹腔注射,染毒7d,采用小鼠精子畸形实验方法及小鼠骨髓嗜多染红细胞(PCE)微核实验方法进行处理.结果显示小鼠体重、睾丸重量、精子活力、精子畸形率和PCE微核率均趋向:未处理的生产废水>已处理的生产废水>生产用水.结果说明生产用水、未处理和已处理的生产废水都具一定的生殖毒性和致突变性,且已处理的生产废水仍具有较高的生殖毒性.
To study the toxicity of non-volatile organic chemicals on reproduction toxicity of male mice, water samples were collected from a chemical plant in Wenzhou. After being adsorbed and concentrated,water samples were investigated by intraperitoneal injection into male mouse for 7 days. The reproductive toxicity was studied by sperm deformity test and PCE micronucleus test. The results were that the effects of those samples on body and testis weight,sperm vital force ,the rate of sperm deformity and the rate of micronucleus are as following:untreated waste water>disposed waste water> production water. While the production water,untreated waste water and disposed waste water all have some reproductive toxicity,the disposed waste water still has a higher reproductive toxicity than the production water.
出处
《浙江大学学报（理学版）》
CAS
CSCD
2004年第3期326-329,共4页
Journal of Zhejiang University（Science Edition）
基金
温州市科技局科研基金资助(S2002A015)
温州市"551"人才基金资助.
关键词
化工厂废水
生殖毒性
精子畸形率
微核率
致突变性
waste water
reproductive toxicity
rate of sperm deformity
rate of micronucleus
