扬州市性传播疾病患者支原体、衣原体、淋病奈瑟菌及阴道加特纳菌感染情况的研究

Studies on the infection status of seven species Mycoplasma, three species of Chlamydia, Neisseria gonorrhoeae and Garderella vaginalis in 76 patients with sexual transmitted diseases

目的 研究扬州市男性性传播疾病(STD)患者支原体、衣原体、淋病奈瑟菌及阴道加特纳菌的感染情况。方法 收集男性STD患者病灶拭子标本进行解脲脲原体(Uu)、人型支原体(Mh)、肺炎支原体(Mpn)、生殖支原体(Mg)、发酵支原体(Mf)、穿通支原体(Mpe)、梨支原体(Mpi)、沙眼衣原体(Ct)、肺炎衣原体(Cpn)、鹦鹉热衣原体(Cps)、淋病奈瑟菌(Ng)和阴道加特纳菌(GV)等12种病原体作巢式聚合酶链反应(nPCR)检测,并对Ng阳性者进行了产青霉素酶淋病奈瑟菌(PPNG)检测。结果 Un、Mh、Mpn和Mg 4种支原体阳性率分别为64.5％、27.6％、26.3％、18.4％,Mf和Mpe为2.6％,Mpi未检出;Ct为31.6％,Cpn和Cps无阳性病例检出;Ng为36.8％,其中PPNG占14.3％;GV阳性率为15.8％。淋球菌阳性的男性STD者与淋球菌阴性者中支原体核酸检出率差异有显著性(X^2=3.848,P<0.05)。结论 扬州市男性STD患者支原体、衣原体、淋病奈瑟菌、阴道加特纳菌感染率较高。在临床诊疗中应重视淋球菌、衣原体、支原体和阴道加特纳菌的检测,使患者能获得正确诊断与合理治疗。

Obejctive To study the infectious status of seven species of Mycoplasma, three species of Chlamydia, Neisseria gonorrhoeae and Garderella vaginalis in the 76 male sexual transmitted disease (STD) patients in Yangzhou city. Methods Tweelve species of pathogens including Ureaplasma urealyticum (Uu), Mycoplasma hominis (Mh), Mycoplasma pneumoniae (Mpn), Mycoplasma genitalium (Mg), Mycoplasma fermentans (Mf), Mycoplasma penetrans (Mpe), Mycoplasma prium (Mpi), Chlamydia trachomatis (Ct), Chlamydia pneumoniae (Cpn), Chlamyia psittaci (Cps), Neisseria gonorrhoeae (Ng) and Garderella vaginalis (GV) were detected by nested polymerase chain reaction including PPNG. Results The positive rates of Uu, Mh, Mpn, Mg, Mf, Mpe, Ct, Ng were 64. 5%, 27. 6%, 26. 3%, 18. 4%, 2. 6%, 2. 6%, 31. 6%, 36. 8%, in which Penicillinase--producing neissevia gonorrhoeae (PPNG) accounted for 14. 3%, GV 15.8%. No Mpi, Cpn or Cps were found. There was more significant therapeutic effects on the detectable rate of Mycoplasms nucleic acid between positive gonococcus and negative gonococcus in male STDs patients (X^2 = 3. 848, P< 0. 05). Conclusion The infection rates of Mycoplasma, Chlamydia, Ng and GV were high among male STD patients in Yangzhou city. In clinical practice, more attention should be paid on correct diagnosis and treatment for patients, with Gonococcus,Chlamydia,Mycoplasma and GV.