肝移植治疗晚期原发性肝癌的初步报告

Liver transplantation for advanced primary hepatocellular carcinoma

目的 探索晚期肝癌行同种原位肝移植的治疗价值。方法 收集我院 2 0 0 0年 8月～2 0 0 2年 2月进行的 36例肝移植的临床资料 ,对其中 15例晚期肝癌的临床资料进行分析 ,并对其中手术后出院的 13例进行随访。结果 1年生存率 85 .7% (6 7) ,有 1例 6个月内因肝癌复发转移而死亡 ;至 2 0 0 2年 2月 ,无瘤生存 10例 ,最长 19个月 ,最短 5个月 ;带瘤生存 2例 ,1例生存 19个月 ,1例生存 10个月。结论 根据我国国情 ,只要患者经济状况允许 ,无肝外转移的晚期肝癌仍是目前我国肝移植的适应证。

Objective To investigate the value of liver transplantation for late hepatocellular carcinoma. Methods Thirty six patients were treated by liver transplantation from August 2000 to February 2002, of which 15 patients had had advanced hepatocellular carcinoma and thirteen of these 15 patients were evaluated for results. Results The 1 year survival rate was 86%(6/7). Only one patient died of recurrence within 6 months. The tumor free survival was 5 to 19 months. Till February 2002, two patients have survived for 10 months and 19 months with recurrence. Conclusion In our country, if the patients can afford liver transplantation, advanced hepatocellular carcinoma without extrahepatic metastasis is still indicated for liver transplantation , since some patients may survive relatively long. [