CT与肿瘤标记物对非小细胞型肺癌N_2淋巴结转移的预测作用探讨

The prognostic action of chest computed tomographic(CT) and tumor marker of non small lung cancer N 2 lymphatic metastasis

目的 :回顾性地探讨CT与肿瘤标记物结合能否提高对非小细胞性肺癌N2 淋巴结转移的诊断率。方法 :将 1996～ 1999年支气管肺癌、CT诊断为N0～ 1淋巴结转移并行手术治疗的病人 ,术后根据病理结果重新分期为N0～ 1和N2 ;根据两组中血清 β2 -MG、CEA水平变化进行对照分析 ;结果 :肿瘤的大小、β2 -MG、CEA对CT诊断有一定的补充作用 ;结论 :CT扫描对N2 淋巴结转移有较高的预测作用 ,当不能确认N2 转移时 ,肿瘤的大小、β2 -MG、CEA是一种有效的补充。

Objective:although the low sensitivity of chest computed tomographic(CT) scan in the diagnosis of N 2 disease.We retrospectively studied the patients with CT scans and tumor marker cann′t advance versus non small cell lung cancer N 2 lymphatic metastasis rate.Methods:Method Between 1996 and 1999,362 patients with lung cancer who had CT diagnose preoperative N O 0～1 disease underwent surgical resection of lung cancer.Postoperative according to pathology outcome anew staging N 0～1 and N 2;two group in blood serum β 2-micrglobulin(β 2-MG)、carcinoembryonic antigen(CEA) level change progression contrast analysis;Results:That tumorous size、serum β 2-MG,CEA level and CT diagnose have got definite renew our supplies of action;Conclusion:CT scan N 2 metastasis has higher prognostic action,the instant cannot diagnose N 2 metastasis.It was a kind of virtual supplement that tumorous size,serum β 2-MG、CEA.