慢性充血性心力衰竭患者的甲状腺功能病态综合征

Euthyroid sick syndrome in chronic congestive heart failure patients

目的 探讨慢性充血性心力衰竭患者甲状腺功能病态综合征 (ESS)的存在特点。方法 检测 30例慢性充血性心力衰竭患者 (心衰组 )及 2 7例健康者 (对照组 )的血清甲状腺素 (T4)、三碘甲状腺原氨酸 (T3 )、游离T4、游离T3 以及促甲状腺激素 (TSH)。结果 慢性充血性心衰患者血清T3 、游离T3 较健康对照组下降 (P <0 .0 1) ,而血清T4、游离T4、TSH在两组间的差异无统计学意义。结论 中至重度慢性充血性心衰患者可合并病态甲状腺功能状态 。

Objective To evaluate the presence of euthyroid sick syndrome(ESS) in chronic congestive heart failure(CCHF) patients.Methods Serum concentrations of triiodothyronine(T 3),thyroxine(T 4) and thyroid-stimulating hormone (TSH) were measured in 30 patients with CCHF (NYHA Ⅱ-Ⅳ) (heart failure group) and 27 volunteers(controlgroup).Results T 3 and free T 3 in the CCHF patients were lower than those of control group(P< 0.01),while T 4,free T 4,TSH showed no significant differences between the two groups.Conclusion Moderate-to-severe CCHF patients complicated with ESS,and ESS is an index for unfavourable prognosis of CCHF.