期刊文献+

贯叶连翘醇提条件的多指标优化 被引量:14

MULTI-INDICES OPTIMIZATION OF THE EXTRACT CONDITIONS OF HYPERICUM PERFORATUM L.(ST.JOHN'S WORT)USING ALCOHOL AS SOLVENT
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摘要 本研究采用超声波提取法 ,对贯叶连翘中总黄酮、金丝桃素类和贯叶金丝桃素等主要有效成分在醇提过程中的提取条件 (溶媒种类、浓度、提取时间等 )进行了考察。结果表明 ,以总黄酮和金丝桃素类化合物为指标 ,用 6 5 %~ 80 %的乙醇水溶液超声提取 30min ,提取效率较高 ;以贯叶金丝桃素为指标 ,则以用 75 %~90 %的甲醇提取 30min效果较好。 Using alcohol aqueous solutions as extract solvents,we investigated the extract efficiency of the main effective ingredients from Hypericum perforatum L. (St. John's Wort) under ultrasonic extraction with several conditions,such as the kinds and the concentration of alcohols,the extract time. The results showed that the best extract solvent for flavonoids and hypericins is 65%~80% ethanol aqueous solution,while for hyperforin,the solvent is 75%~90% methanol aqueous solution. The best ultrasonic extract time is about 30 minutes for three types of the effective ingredients.
出处 《天然产物研究与开发》 CAS CSCD 2004年第2期149-152,共4页 Natural Product Research and Development
基金 国家教育部高等学校骨干教师资助基金项目 ( 2 0 0 0 ) 广州市科技局重大项目 ( 2 0 0 0 2 10 1 0 1)
关键词 贯叶连翘 总黄酮 贯叶金丝桃素 金丝桃素 提取工艺 植物药 Hypericum perforatum extract condition hypericin hyperforin flavonoids
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参考文献9

  • 1Jeffrey MG, Britt S. St. John's wort(Hypericum perforatum ): A review of the current pharmacological, toxicological, and clinical literature. Psychopharmacology, 2001,153(4) :402-414
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