反复流产与抗心磷脂抗体关系的探讨

Study on the relationship between repeating abortion and anticardiolipin antibody(ACA)

目的 探讨反复流产、宫内死胎 ,孕中、晚期孕妇与抗磷脂自身抗体的关系。方法 采用ELISA方法对 1934例患者进行ACA -IgG、ACA -IgM抗体测定。结果 表明有反复流产、宫内死胎史患者血中ACA阳性检出率为 30 .2 9%。正常早中晚妊娠妇女阳性率为 5 .11% ,检出阳性者中多为先兆流产、宫内发育迟缓及轻度妊高征。结论 ACA阳性与反复流产、宫内死胎、先兆流产、宫内发育迟缓有密切关系。

Objective: The level of ACA was tested in cases with repeating abortion and dead embryo and in the normal pregnancy to explore their reationship on antibody. Method: Enzyme linked immunosolid assay(ELISA)was used to detect the lovel of ACA-IgM, CAC-IgG in 1934 cases. Result: The ACA positive rate in repeating abertion and doad embryo cases was 30.29%. In the normal pregnant cases was 5.11%, most of which belong to introrterus retarded levelopmentor hyprtensul syhdrome in pregnancy. Conclusion: ACA positise is closely connected with repeating abortion,dead embryo and introuterus retarded develpment.