吸毒者肺谷物性肉芽肿尸检2例光镜及电镜观察

Pulmonary corn starch granulomas in drug users: light and electron microscopic changes of 2 autopsied cases

目的 报告 2例吸毒致死者肺谷物性肉芽肿。方法 应用光镜、电镜及组织化学方法 ,对肺谷物性肉芽肿的形态学及组织化学特征进行分析 ,并结合文献复习对肺谷物性肉芽肿的形成机制进行初步讨论。结果 肺谷物性肉芽肿甲基紫、刚果红强阳性 ,光镜及电镜下具有特征性的马尔他十字结构。结论 吸毒者肺谷物性肉芽肿形成与非静脉注射性毒品中的添加剂有关 。

ObjectiveTo report two cases of pulmonary corn starch gra nulomas in drug users MethodsThe morphologic and histochemistric features were analyzed by light and electron microscopy, combined with the literature review to make an inqu iry for the probable histogenesis of pulmonary corn starch granuloma ResultsMethyl violet and Congo red stain showed strong positive, and had Maltese-cros s structure in this granulomas ConclusionThe formation of pulmonary corn starch granuloma is related to deposition of drug additive in non-vein-injective drugs. Meanwhile, diagnosis of this granulom a should be differentiated from other type of granulomatous lesions in lung