期刊文献+

免疫组化在肝细胞肿瘤诊断中的应用 被引量:8

Role of immunohistochemistry in diagnosis of hepatocytic tumors
下载PDF
导出
摘要 肝细胞癌 (HCC)与肝内胆管癌 (ICC)及转移性腺癌 (MAC)的鉴别诊断是外科病理诊断中常遇到的难题 ,HepPar 1是目前肝细胞分化标记物中最敏感且具特异性的一种阳性标记物 ,可结合其他抗体 ,如CD3 4、pCEA、AFP、CK19和MOC3 1等用于日常HCC。
出处 《诊断病理学杂志》 CSCD 2004年第1期53-56,I013,共5页 Chinese Journal of Diagnostic Pathology
  • 相关文献

参考文献26

  • 1丛文铭,吴孟超.小肝细胞癌的临床病理特点:附93例分析[J].中华肿瘤杂志,1993,15(5):372-374. 被引量:35
  • 2Kakar S,Muir T,Murphy LM, et al.Immunoreactivity of Hep Par 1 in hepatic and extrahepatic tumors and its correlation with albumin in situ hybridization in hepatocellular carcinoma[J].Am J Clin Pathol,2003,119(3):361-366.
  • 3Zimmerman RL,Burke MA,Young NA,et al.Diagnostic value of hepatocyte paraffin 1 antibody to discriminate hepatocellular carcinoma from metastatic carcinoma in fine-needle aspiration biopsies of the liver[J].Cancer,2001,93(4):288-291.
  • 4Chu PG,Ishizawa S,Wu E, et al.Hepatocyte antigen as a marker of hepatocellular carcinoma:an immunohistochemical comparison to carcinoembryonic antigen,CD10,and alpha-fetoprotein[J].Am J Surg Pathol,2002,26(8):978-988.
  • 5Ohmori S,Shiraki K,Sugimoto K, et al.High expression of CD34 positive sinusoidal endothelial cells is a risk factor for hepatocellular carcinoma in patients with HCV-associated chronic liver diseases[J].Hum Pathol,2001,32(12):1363-1370.
  • 6Tsuji M,Kashihara T,Terada N, et al.An immunohistochemical study of hepaticatypical adenomatous hyperplasia,hepatocellular carcinoma and cholangiocarcinoma with alpha-fetoprotein,carcinoembryonic antigen,CA 19-9,epithelial membrane antigen, and cytokerati
  • 7Shimonishi T,Miyazaki K,Nakanuma Y.Cytokeratin profile relates to histological subtypes and intrahepatic location of intrahepatic cholangiocarcinoma and primary sites of metastatic adenocarcinoma of liver[J].Histopathology,2000,37(1):55-63.
  • 8Leong AS, Sormunen RT,Tsui WM, et al.Hep Par 1 and selected antibodies in the immunohistological distinction of hepatocellular carcinoma from cholangiocarcinoma,combined tumous and metastatic carcinoma[J].Histopathology,1998,33(4):318-324.
  • 9Fasano M, Theise ND,Nalesnik M, et al.Immunohistochemical evaluation of hepatoblastomas with use of the hepatocyte-specific-marker,hepatocyte paraffin 1,and the polyclonal anti-carcinoembryonic antigen[J].Mod Pathol,1998,11(10):934-938.
  • 10Lamps LW,Folpe AL.The diagnostic value of hepatocyte paraffin antibody 1 in differentiating hepatocellular neoplasms from nonhepatic tumors:a review[J].Adv Anat Pathol,2003,10(1):39-43.

二级参考文献6

共引文献60

同被引文献101

  • 1梁玉梅,李向红,吕亚莉,钟梅.肝脏梭形细胞恶性肿瘤的临床病理及免疫组织化学特点[J].中华医学杂志,2005,85(2):96-100. 被引量:7
  • 2吴孟超,张柏和.我国肝脏外科现状和发展前景[J].中华外科杂志,1996,34(9):515-517. 被引量:45
  • 3Wudel LJ Jr,Chapman WC.Indications and limitations of liver transplantation for hepatocellular carcinoma.Surg Oncol Clin N Am 2003;12:77-90,ix.
  • 4Soresi M,Magliarisi C,Campagna P,Leto G,Bonfissuto G,Riili A,Carroccio A,Sesti R,Tripi S,Montalto G.Usefulness of alpha-fetoprotein in the diagnosis of hepatocellular carcinoma.Anticancer Res 2003;23:1747-1753.
  • 5Wennerberg AE,Nalesnik MA,Coleman WB.Hepatocyte paraffin 1:a monoclonal antibody that reacts with hepatocytes and can be used for differential diagnosis of hepatic tumors.Am J Pathol 1993;143:1050-1054.
  • 6Chu PG,Ishizawa S,Wu E,Weiss LM.Hepatocyte antigen as a marker of hepatocellular carcinoma:animmunohistochemical comparison to carcinoembryonic antigen,CD10,and alpha-fetoprotein.Am J Surg Pathol 2002;26:978-988.
  • 7Sutcliffe R,Maguire D,Murphy P,Portmann B,Rela M,O'Sullivan G,Mufti G,Heaton N.Detection and clinical significance of bone marrow micrometastases in patients undergoing liver transplantation for hepatocellular carcinoma.Transplantation 2005;80:88-94.
  • 8Lau SK,Prakash S,Geller SA,Alsabeh R.Comparative immunohistochemical profile of hepatocellular carcinoma,cholangiocarcinoma,and metastatic adenocarcinoma.Hum Pathol 2002;33:1175-1181.
  • 9Tanaka K,Honna T,Kitano Y,Kuroda T,Tanaka K,Morikawa N,Matsuda H,Kawashima N,Matsuoka K,Miyauchi J.Combined fibrolamellar carcinoma and cholangiocarcinoma exhibiting biphenotypic antigen expression:a case report.J Clin Pathol 2005;58:884-887.
  • 10Minervini MI,Demetris AJ,Lee RG,Carr BI,Madariaga J,Nalesnik MA.Utilization of hepatocyte-specific antibody in the immunocytochemical evaluation of liver tumors.Mod Pathol 1997;10:686-692.

引证文献8

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部