超声导向瘤内注射无水酒精治疗肝癌

Percutaneous Intra-tumor Injection of Pure Ethanol for Liver Cancer under Ultrasonographic Guidance

目的 探讨超声导向瘤内注射无水酒精治疗肝癌的疗效。 方法 利用B超引导经皮肝穿刺瘤内注射无水酒精治疗原发性、转移性肝癌 6 0例 ,共注射 4 5 0次。 结果 癌肿直径 <3cm、3～ 5cm、>5cm病人 ,1年和 3年的生存率分别为 10 0 %、6 8.8% ,89.7%、4 8.3%和 83.3%、13.3%。 73.3%(4 4 6 0 )肿瘤缩小 ,AFP阳性患者 97.7% (4 3 4 4 )出现AFP下降或转阴 ,未发生肿瘤沿针道转移及严重并发症。 结论 该方法操作简单、适应证广、副作用少 ,疗效确切。

Objective To evaluate the clinical efficiency of intra tumor injection of pure ethanol under the guidance of ultrasonography. Methods 60 cases of liver cancer were treated with the percutaneous ethanol injection therapy(PEIT) under the guidance of ultrasonography, 450 times of the injection were subjected totally. Results The results showed that the 1 and 3 year survival rate of patients with tumor of <3 cm, 3～5 cm diameter, and >5 cm diameter was 100% and 68.8%, 89.7% and 48.3%, 53.3% and 13.3% respectively. The tumor mass shrank in 73.7%(44/60) patients, and 97.7%(43/44) patients were associated with decline or return to normal of the AFP. No metastasis through the needle track or other serious complications had beed encountered. Conclusion Technically simple and wide range of application, minimal trauma and effectiveness are the characteristics of this method.