局部亚低温对脑出血患者临床疗效及脑水肿的影响

Clinical observation of the effect of the local mild hypothermia auxiliary therapy on cerebral hemorrhage

目的 :研究观察应用局部亚低温治疗重症脑出血患者临床疗效及对脑水肿的影响。方法 :随机将 74例脑出血患者分为治疗组 36例和对照组 38例 ,治疗组在药物综合治疗基础上加用局部亚低温治疗 ,对照组为单纯药物综合治疗 ,治疗开始前及治疗后 2 1天分别进行神经功能缺损评分和脑血肿、脑水肿体积对比观察。结果 :治疗 2 1天后 ,治疗组的神经功能评分明显低于对照组 (P <0 .0 5 ) ;治疗组脑水肿体积较对照组明显减少 ,两组有显著差异 (P <0 .0 1) ;两组血肿体积无显著性差异 (P >0 .0 5 )。结论 :局部亚低温可促进脑出血患者的神经功能恢复、明显改善预后及减轻脑水肿作用。

Objective:To observe the effect of the local mild hypothermia therapy on severe cerebral hemorrhage.Methods:74 patients were divided into two groups, treatment group (36 cases) and control group (38 cases). Regular treatment was used in both groups, and the local mild hypothermia therapy was just applied in treatment group. Neural function scale, cerebral hematoma and cerebral edema were observed before treatment and 21 days after treatment.Results:Neural-function scale and cerebral edema in treatment group decreased significantly after treatment at 21d (P<0.05), compared with those in control group. Cerebral hematoma have no remarkable difference in two groups (P>0.05).Conclusion:The local mild hypothermia therapy can promote the neural-function recovery,significantly improve prognosis and reduce cerebral edema in cerebral hemorrhage patients.