摘要
采用~3H-TdB掺入实验,测定黄芪刺五加对人卵巢癌细胞DNA合成的抑制作用。结果该药能直接抑制癌细胞DNA的合成,并随用药剂量的增加、用药时间的延长,抑制作用增强。为临床应用提供了药效基础。
An assay of ~3H-thymidine incorporation was performed for measuring the inhibi-tory effect of Astragalus, Acanthopanax Senticosus (A-AS) on DNA synthesis ofhuman ovarian cancer cells. A positive result was showed in this study. The higherthe dose of A-AS or the longer the exposure of ovarian cancer cells to A-AS, thegreater the inhibitory degree of proliferation of the cancer cells. This study providesan evidence of the pharmaoodynamio aotion of A-AS for the further clinical applica-tion.
出处
《肿瘤》
CAS
CSCD
北大核心
1992年第2期51-52,共2页
Tumor