59例宫颈癌伴发其他原发癌临床分析

CERVICAL CARCINOMA OF UTERUS WITH OTHER PRIMARY CARCINOMA——REPORT OF 59 CASES

本文报道我院1962～1989年收治59例宫颈癌伴发其他原发癌,结合文献对其病因、发生部位和治疗进行讨论。多原发癌71.2％发生在生殖系统和消化系统,该两系统是多原发癌的易感器官,由于原发癌和复发转移癌两者处理预后截然不同,第二原发癌如能及时发现、正确处理,采用手术或放疗,辅以化疗,疗效良好。本文病例三年、五年生存率分别为35.3％及21％。

Among 17250 cases of cervical canser treated at Shanghai Cancer Hospital from1962 to 1989, 59 were found to have developed multiple primary malignant tumors and71.2% of them had their second primary malignancies at the female gentital tract andgastrointestinal tract. Fifty six cases were found to have second primary carcinomasafter treatment of cervical cancer and three were before. The carcinogenic factors werediscussed. The combination of surgery, radiotherapy and chemotherapy was used in themanagement of the second primary carcinomas. In this series, the three and five-yearsurvival rates were 35.3% and 21%, respectively.