静脉滴注阿奇霉素替硝唑治疗急性盆腔炎的疗效观察

The efficacy of azithromycinin and tinidazole for injection in the treatment of acute pelvic inflammatory disease

目的 了解乳糖酸阿奇霉素对急性盆腔炎的治疗效果。方法 治疗组 ( 3 0例 )用注射用乳糖酸阿奇霉素 5 0 0mg/次、替硝唑 2 5 0ml/次静脉滴注 ,每日 1次 ;对照组 ( 3 0例 )用 0 .5 %甲硝唑 2 5 0ml/次、氨苄青霉素 3 g/次静脉滴注 ,每日 2次 ;均以 6～ 10天为一个疗程。结果 治疗组有效率为 93 .3 % ( 2 8/3 0 ) ,对照组为 73 .3 % ( 2 2 /3 0 ) ;平均疗程治疗组为 7.5± 1.5天 ,对照组为 10 .5± 2 .5天。两组比较 ,治疗组有效率显著高于对照组 (P <0 .0 5 ) ,疗程显著短于对照组 (P <0 .0 1)。结论 注射用乳糖酸阿奇霉素加替硝唑是治疗急性盆腔炎安全有效的药物。

Objective To evaluate the efficacy of using azithromycinin lactobionate for injection to treat acute pelvic inflammatory disease. Methods The treatment group received azithromycinin lactobionate and tinidazole for injection(one in dose of 500mg and 250ml,qd for 6～10 d); the control group received metronidazole and ampicillin (one in dose of 250ml and 3g,qd for 6～10 d).Results The quality of therapeutic drug was less than that of comparative drug, the efficacy rate of treatment group was better than that of control group. The occurrence rate of adverse event of experimental group was lower than that of comparative group.Conclusion Azithromycinin lactobionate for injection is an effective and safe agent in the treatment of acute pelvic inflammatory disease.