芴胺衍生物荧光有机染料的合成

Synthesis of Fluorescent Organic Dyes

含吸电子或供电子取代基的卤代芴包括溴代芴和碘代芴 ,利用钯催化 ,可在温和的条件下与一胺、二胺及手性胺进行C Ncoupling反应 ,生成相应的芴胺衍生物。该类化合物多为具有很强荧光的荧光染料。

Both electron-rich and electron-deficient fluorene bromides and fluorene iodies can be converted by Pd-catalysed C-N coupling with primary、secondaly and chiral amines into a series of corresponding fluorene amines in good yields.