米索前列醇在宫腔镜检查中的作用及其评价

Effects and evaluation of misoprostol in hysteroscopy

目的 :观察米索前列醇在宫腔镜检查时软化宫颈及镇痛的效果。方法 :将宫腔镜检查的 10 7例病人随机分为 2组 :米索前列醇组 6 3例 ,检查前 1h口服米索前列醇 2 0 0 μg,对照组 4 4例不施任何药物。结果 :宫腔镜检查米索前列醇组宫口扩张直径、术中出血、人工流产综合症 (PAAS)发生率及腹痛程度均明显低于对照组 (P <0 .0 5 )。结论 :宫腔镜检查前 1h口服米索前列醇 2 0 0 μg 为方便、有效软化宫颈的理想方法 ,可缓解有创检查性疼痛 ,减少手术操作 ,减少术中出血 ,降低PAAS的发生 ,值得临床推广应用。

AIM : To observe the effects of misoprostol used for intenerating cervical and ease pain in hysteroscopy. METHODS : 63 of 107 cases were randomly chosen as the group of misoprostol, and 200 μg misoprostol was taken orally 1h before hysteroscopy. Another 44 cases were taken as the group of antitheses, and no medication was taken before hysteroscopy. RESULTS : The diameter of cervical, hemorrhage, the rate of PAAS and bellyache in the group of misoprostol were lower than that in the group of antitheses. CONCLUSION : 200 μg misoprotol orally 1h before hysteroscopy is an advantageous and ideal method with alleviating pain from wound, reducing manipulation, decreasing hemorrhage, reducing PAAS happening in intenerating cervical.