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脑蛋白水解物治疗糖尿病周围神经病变的临床疗效 被引量:11

Effect of cerebroprotein hydrolysate on diabetic peripheral neuropathy
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摘要 目的观察脑蛋白水解物治疗糖尿病周围神经病变的临床疗效。方法 10 5例糖尿病神经病变患者随机分为治疗组(3 4例 )、标准对照组 (3 8例 )和空白对照组 (3 3例 ) ,分别给予静脉注射脑蛋白水解物、肌肉注射弥可保联合静脉注射爱维治和口服B族维生素治疗 ,观察各组患者的疗效。结果静脉注射脑蛋白水解物能够改善临床症状 ,提高神经传导速度 ,与肌肉注射弥可保联合静脉注射爱维治治疗效果基本相同。结论脑蛋白水解物能够用于糖尿病神经病变治疗。 ObjectiveTo investigate the effect of cerebroprotein hydrolysate on diabetic peripheral neuropathy.Methods105 diabetic patients were randomly divided into the treatment group (34 cases, treated with intravenous injection of cerebroprotein hydrolysate), standard control group (38 cases, treated with intramuscular injection of Metrycobal combined with intravenous injection of Actovegin) and blank control group (33 cases, treated with oral vitamin B1, B6, B12). Curative effects of three groups were evaluated.ResultsIt was shown that intravenous injection of cerebropotein hydrolysate could improve patients' symptoms, raised speed of nerve conduction and its curative effect was as same as intramuscular injection of Metrycobal combined with intravenous injection of Actovegin.ConclusionIntravenous injection of cerebropotein hydrolysate has a curation effect on diabetic peripheral neuropathy.
出处 《中国康复理论与实践》 CSCD 2004年第4期229-230,共2页 Chinese Journal of Rehabilitation Theory and Practice
关键词 糖尿病 神经病变 脑蛋白水解物 diabetes neuropathy cerebropotein hydrolysate
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  • 1Feldman EL, Stevens MJ, Greene DA. Treatment of Diabetic Neuropathy[M].Chicago:Mosby Year Book,1994.393-428.
  • 2King GL, Brow NM. The cellular and molecular mechanisms of diabetic complication[J].Endocrinal Metabelin North Am,1996,25(2):255-270.
  • 3Troni W, Carta Q, Cantello R, et al. Peripheral nerve function and metabolic control in diabetes mellitus[J].Ann Neurol,1984,16:178-183.
  • 4郭玉璞.糖尿病神经系统并发症[A].见:刘新民主编.实用内分泌学[C] 第2版[C].北京:人民军医出版社,1997.315-321.

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