摘要
目的 探讨中国汉族人群癔症患者与 5 HT2A受体基因T10 2C多态性之间的关系。方法 采用AmP RFLP方法 ,检测癔症患者和对照组的 5 HT2A受体基因频率。结果 5 HT2A受体基因多态性与癔症患者未见明显相关。结论 5 HT2A受体基因不是癔症发病的危险因素。
Objective To assess the association between the gene polymorphism of the serotonin type 2A(5-HT 2A receptor) and hysteria.Methods The association between gene polymorphism of 5-HT 2A receptor and hysteria was determined with amplification restriction fragment length polymorphism technique in healthy persons and 318 hysteria patients.Results There were no significant differences on the frequency of gene type and allele of 5-HT 2A receptor between the healthy group and patient group.Conclusion These results indicate that there is no association between the gene polymorphism of 5-HT 2A receptor and hysteria.
出处
《山东精神医学》
2004年第2期69-70,共2页
Shangdong Archives of Psychiatry