2003年沿淮灾区钩端螺旋体病流行病学监测

Epidemiologic monitoring of Leptospriosis in the flood-affected areas along Huai river of Anhui province

目的 研究沿淮灾区钩端螺旋体病特征 ,为预防灾后钩端螺旋体病爆发流行提供依据。方法 血清学检测采用MAT法 ,动物抗原检测采用RT -PCR ,病原学应用柯索夫培养基分离。结果 沿淮灾区钩端螺旋体病血清群以黄疸出血群为主 ,占 83.33% ,与 2 0世纪 70年代相比出现南黄北移现象。其中怀远县阳性率最高 ,为 1 0 .34%。鼠密度为 8.88% ,带菌率为 2 5 .0 0 %。结论 沿淮灾区钩端螺旋体病以黄疸出血群为主 ,病死率高 ,应引起足够的重视 ,同时要采取灭鼠。

Objective Big flood took place in June ,2003 along the Huaihe River basin.In order to prevent from erupting and prevailing leptospirosis after the calamity,we carried on the on-the-spot investigation and epidemic situation monitoring along the disaster area of the Huaihe River and took the corresponding precautionary measures according to the result. Methods MATwas used in serum detect,RT-PCR in antigen detect and Korthof in cultivate.Results Icterohaemorrhagie of leptospirosis accounted for 83.33%.Among the disaster area,positive rate (10.34%) was the highest ,mouse density was 8.88%,infective rate 25% respectively in Huaiyuan County. Icterohaemorrhagie converted from South to North. Conclusions Icterohaemorrhagie was prominent along the disaster area of the Huaihe River.In view of high fatality rate,we should pay attention to it and adopt the corresponding precautionary measures such as rot control,immunization injection and oral doxycycline ,etc.