风疹爆发应急接种的预防效果研究

Evaluation of Prevention Effectiveness of Emergent Vaccination for Rubella Outbreak

目的 探讨风疹应急性预防接种的效果 ,为控制风疹爆发疫情提供依据。方法 对某市 8所小学风疹爆发流行进行流行病学调查 ,首先利用 1所小学自然爆发至终止的数据建立本次风疹爆发的Reed -Frost模型 ,以此模型预测其它 7所经应急性预防接种的小学的理论风疹发病人数 ,进而预测应急性预防接种的预防效果。结果 7所小学风疹的理论显性发病例数 1 0 0 0例 ,应急性预防接种减少风疹发病 92 5例。结论 在发生风疹爆发的小学应尽早进行风疹疫苗的应急接种 。

Objective To evaluate prevention effectiveness of emergent vaccination for rubella outbreak. Methods We investigated rubella outbreak in 8 primary schools and conducted emergent vaccination among 7 primary schools in a middle city of southeast China. At first, a Reed-Frost model was set up using a primary school data and then, we predicted the cases of rubella in other 7 schools by Reed-Frost Model. Results The number of expecting cases and being prevented cases was 1000, 925 respectively in 7 primary schools. Conclusions The emergent vaccinating should be taken as soon as possible when the rubella outbreaks occur in order to prevent spread of the outbreak.