乙型肝炎免疫球蛋白预防乙型肝炎宫内感染疗效研究

A study of effect preventing hepatitis B virus intranterine infection by HBIG

目的:探讨孕妇肌注HBIG对阻断HBV宫内感染的疗效。方法:将101例HbsAg(+)的孕妇分为两组,一组以HBIG肌注,一组作为对照,测新生儿HbsAg、HbsAb。结果:治疗组HbsAg(+)检出率低于对照组,两组差异有显著性(P<0.05)。治疗组对双阳组阻断效果明显,与对照组相比,差异有显著性。结论:HBIG能有效阻断HBV宫内感染。

Objective To explore the effect obstracting HBV intracterine infection by injected HBIG to Pregnancy women.Methods 101 pregnancy women were divided into two groups. Study group used HBIG ,control group not,to determine infants born in HBsAg and HbsAb. Results ①HBV intranterin infection in the study group was lower than that in the control group.This difference was statitiscally significant (P<0.05). ②In the study group HBsAg(+);HbeAg(+)effect was better than that in the control group.This difference was statitiscally sighficant(P <0.05) Conclusion HBIG can prevent HBV intranterine infection