肝硬变并发门脉高压性胃病的研究

Study of portal hypertensive gastropathy in the patients with hepatocirrhosis

目的 探讨肝硬变并发门脉高压性胃病的情况。方法 对 390例门诊及住院的肝硬变患者常规进行胃镜检查 ,并对不同肝功能水平患者门脉高压性胃病发生情况进行回顾分析。结果 390例肝硬变患者中 ,食管 胃底静脉曲张 330例 (84 .6 % ) ;门脉高压性胃病发生率 4 9.2 % (192例 )。根据Child Pugh分级将肝功能分为A、B、C 3级 ,随肝功能级别增加门脉高压性胃病发生率随之增加 ,随食管 胃底静脉曲张严重程度上升 ,门脉高压性胃病发生率亦呈上升趋势 (P <0 .0 5 )。结论 门脉高压性胃病随肝功能分级增加而上升 ,随食管 胃底静脉曲张严重程度的增加而上升 ,对肝硬变患者应常规胃镜检查。

Objective To study portal hypertensive gastropathy in patients with hepatocirrhosis.Methods Gastroscopy was performed in 390 cases with hepatocirrhosis in outpatients and inpatients and the portal hypertensive gastropathy in patient with the different levels of liver function was retrospectively analyzed.Results Of all 390 patients,330 had varicosity of esophagus-fundus(84.6%),and 192 cases(49.2%) had portal hypertensive gastropathy which was classified into A,B and C grades according to Child-Pugh.The incidence rate of portal hypertensive gastropathy was increasing with the increased grade of liver function and was on an increasing trend with the increased severity of varicosity of esophagus-fundus(P<0.05).Conclusion The incidence rate of portal hypertensive gastropathy is increasing with the increased grade of liver function and with the increased severity of varicosity of esophagus-fundus.Gastroscopy is necessary for the patients with hepatocirrhosis as routine.