摘要
目的 测定普通级、SPF级SD大鼠 ,Wistar大鼠血液生化常值并进行比较。方法 日立 715 0全自动生化分析仪自动检测。结果 SPF级与普通级SD大鼠丙氨酸转氨酶、白蛋白、碱性磷酸酶、尿素氮、肌酐、铁、磷、镁、尿酸、低密度脂蛋白、胆汁酸差异有非常显著性 (P <0 0 1) ;SPF级与普通级Wistar大鼠总蛋白、白蛋白、碱性磷酸酶、总胆固醇、甘油三脂、尿素氮、乳酸脱氢酶、磷、镁、尿酸、高密度脂蛋白、胆汁酸 (P <0 0 1) ,低密度脂蛋白 (P <0 0 5 )差异有非常显著性。结论 不同微生物学环境对SD、Wistar大鼠血液生化常值有较大影响。
Objective To measure and compare the normal values of blood routine examination in conventional,SPF SD and Wistar rats.Methods Hitachi-7150 was used in this experiment. Results The ALT,ALB,ALP,BUN,CRE,Fe,P,Mg,UA,LDL,PBA in conventional and SPF SD rats had very significant difference (P<0.01).The TP,ALB,ALP,CHO,TG,BUN,LDH,P,Mg,UA,HDL, PBA in conventional and SPF Wistar rats had very significant difference(P<0.01),the LDL had significant difference(P<0.05),the ALT,ABG,CRE,Fe,GLU,GOT had little difference(P>0.05). Conclusion Different microbiological background significantly affects the biochemical values of rats.
出处
《中国比较医学杂志》
CAS
2004年第2期94-96,共3页
Chinese Journal of Comparative Medicine