摘要
线栓法大鼠大脑中动脉 (MCA)局灶性脑缺血模型被普遍认为是脑缺血标准动物模型 ,因而许多学者进行了大量的研究 ,但实验过程中仍存在一些值得探讨的问题。本文主要从动物选择 ,麻醉剂选择和方法 ,尼龙线选用、制备、放置方法和深度 ,手术部位选择 ,模型成功评价 ,并发症等方面对该模型进行了探讨。
The intraluminal thread occlusion model in the middle cerebral artery of rats is usually believed a standard animal model of focal cerebral ischemia. A lot of researchs have been made on it. In this article, we have discussions about animal selection, drugs and methods of anesthesia, selection, manufacture and placing methods and depth of lynon thread, selection of surgical site, evaluation of successful model, complication, and so on.
出处
《中国比较医学杂志》
CAS
2004年第2期115-118,共4页
Chinese Journal of Comparative Medicine
基金
安徽省自然科学基金项目 ( 0 0 0 44 116)
