肉苁蓉多糖CDP-4的化学结构研究

Studies on the chemical structure of polysaccharide CDP-4 isolated from Cistanche deserticola

目的 :研究从中药肉苁蓉 (Cistanchedeserticola)肉质茎中得到的中性多糖CDP 4的化学结构。方法 :利用化学方法和谱学方法分析其结构特征。结果 :CDP 4的平均相对分子质量为 1 .4× 1 0 4,由葡萄糖组成 ,由 1 ,4 linkageglcp和 1 ,6 linkageglcp以 3∶1的比例连接组成。结论 :CDP 4为直链葡聚糖 ,空间结构与直链淀粉不同 ,为新的葡聚糖。

Objective: To study the chemical structure of polysaccharide CDP 4 isolated from Cistanche deserticola Y.C.Ma. Methods: The chemical properties of CDP 4 were determined by using chemical method and spectrocospic method. Results: CDP 4 was composed of glucosyl group, with the ratio 1,4 linkage glc p ∶1,6 linkage glc p =3∶1,and its mean molecular weight 1.4 ×10 4. By means of methlylation analysis, complete acid hydrolysis analysis, NMR spectrum, the linkages and sequence information of CDP 4 were obtained. Conclusion: CDP 4 is a new linear glucan.