汉族胎儿与新生儿血红蛋白F中~GΥ/~AΥ比值测定

~Gγ/~Aγ Ratio of Fetal Hemoglobin of Fetuses and Newborns

用Triton X—100酸性尿素聚丙烯酰胺凝胶电泳法测定了385例胎儿与新生儿的血红蛋白F中~Gγ/与~∧γ比值,结果为:三个孕周组(17.1～27.0、27.1～37.0及37.1～43.0)的~Gγ值(％~Gγ)分别为70.3％、70.2％和69.5％,三组间及男女性别间无统计学差异。新生儿~Gγ值分布为:正常~Gγ(53％～79％)占97.6％,低~Gγ(36％～46％)占1.6％和高~Gγ(81％～82％)占0.8％。

~Gγ/~Aγ ratio of fetal hemoglobin in 385 fetuses and newborns in Zunyi was determined belectrophoresis on polyacrylamide gels in urea, acetic acid and Triton X—100. The results showed that the mean ~Gγ was 70. 3%,70. 2% and 69. 5% in three groups (17. 1—27. 0,27.1—37. 0 and 37. 1—43. 0 weeks) respectively. There was no significant difference of Gγ values between male and female groups. The distribution of the ratio is: normal Gγ (53%—79%) 97.6%, low Gγ (36%-46%) 1.6% and high Gγ (81%-82%) 0.8%.