首发首诊住院分裂症患者精神药物使用情况调查

The Investigation on Using the Psychopharmaca to the First-time Happening and First-time Diagnosis In-hospital Schizophrenia Patient

目的 了解首发首诊住院分裂症患者精神药物的使用情况。方法 自 2 0 0 0年全部首次住院病例中 ,选择符合CCMD - 2 -R精神分裂样精神病标准者 6 73例。结果 首选单一用药者 5 87例 (92 .15 % ) ,常用药物依次为氟哌啶醇占 6 4 .5 2 % ,氯氮平占 14 .76 % ,氯丙嗪占 7.6 9% ,舒必利占 2 .83% ,其他药物的使用率均不足 1% ,首选联合用药者 5 0例 (7.85 % ) ,最常见的是氯氮平联合舒必利占 4 .71% ,合用安坦者 5 10例 (80 .0 6 % )。结论 对初治分裂症的首选用药 ,仍以经典抗精神病药为主 ,不应联合用药 ,必要时可合用增效剂 ,氯氮平不宜做为首选用药。

Objective To better understand the results of using psychopharmaca to the first-time happening and first-time diagnosis in-hospital schizophrenia. Methods We have chosen 637 first-time in-hospital cases accorded with CCMD-2-R schizophrenia and the standard of schizophrenifa-like psychosis since 2000. Results We found out that 587 cases(92.15%)have been used single drug, common drugs are haioplridol(4.52%), zapine(14.76%), hlorpromazine (7.69%),sulipride (2.83%) by turns. The rate of using other drugs is less than 1%. 50 cases of firstly choosing to use combined drugs take the percentage 7.85,The common ways are the joint of clozapine and sulipride(4.71%),the joint of clozapine and artane (80.06%)510cases in total. Conclusions To the first-time schizophrenia patient, we suggest mainly using classical antipsychotics instead of combined drug. The combined synergist is available when it is necessary. The clozapine should not be used as firstly chosen drug.