原子吸收分光光度法测定右旋糖酐铁注射液的含量

Determination of iron dextran injection by atomic absorption spectrophotometer

建立了原子吸收分光光度法测定右旋糖酐铁注射液含量的方法,以盐酸溶液(1→100)为溶剂,检测波长248.3nm,在5～20μg/mL范围内吸收度与浓度呈良好的线性关系,r=0.9995,回收率98.8%,RSD为1.5%(n=5),稳定性好。本方法与碘量法相比,操作简便、快速,结果准确。

A method was established for the determination of iron dextran injection by atomic absorption spectrophotometer. The detection was carried out with an ultraviolet detector at 248.3 nm. The linearity was in the range of 2～20 μg/mL with r=0.999 5, the average recovery was 98.8% with 1.5% of RSD. The method was proved to be simple, rapid and precise. This method may be used for the quality control of iron dextran injection.