乳腺叶状囊肉瘤24例临床分析

Clinical analysis of 24 breast cystosarcoma phyllodes cases

目的 探讨乳腺叶状囊肉瘤的临床特点 ,强调外科手术对其治疗的重要意义。方法 对该院1988～ 2 0 0 2年收治的 2 4例乳腺叶状囊肉瘤 ,根据其患者年龄、原发肿瘤大小、有无腋淋巴结转移等因素 ,选择局部包块切除术、单乳切除术或改良根治术等手术方法进行治疗 ,并对术后病理进行组织学分类 ,全组病例均获随访。结果 局部复发 6例 ,远处转移并死亡 2例 ,术后病理高分化 17例 ,中分化 5例 ,低分化 2例 ,5年生存率 91.7%。结论 乳腺叶状囊肉瘤发病率低 ,多数病例病理分化较好 ,病程进展缓慢 。

Objective:To explore the clinical characteristics of breast cystosarcoma phyllodes (CP)and put an emphasis on the significance of surgical treatment .Methods:From 1988 to 2002,24 cases of breast CP were treated in Affiated Hospital of LuZhou Medical College. According to patients age, primary tumor size and axillary or non-axillary lymphnode metastasis, local excision,mastectomy or modified radical mastectomy were employed respectively to treat breast CP. Postoperative pathohistological differentiation was adopted and all cases were followed Results: Of 24 cases,6 were of local recurrence and 2 distant metastasis and died. After operation, 17cases were with high differentiation, 5 medium differentiation and 2 low differentiation in pathology and the survival rate of 5 years is 91.7%.Conclusions:Breast CP is a kind of diease with lower morbidity and most cases with fairly good pathological differentiation and slow disease course and surgical excision is the first choice for treatment.