某铀矿停产十年后原受照工人细胞遗传学效应调查

INVESTIGATION OF CYTOGENETICS EFFECT OF WORKERS EXPOSED TO RADIATION IN A CEASED URANIUM MINE

本文报道了某铀矿停产十年后原140例受照工人的细胞遗传学调查,结果表明其染色体畸变率明显高于对照组(P<0.05)。证明从业工人虽已经过十年机体的自我修复,但内外照射的效应十年后仍可显示出来。水冶、采矿两工种组和1～5、6～10和>10年的三个工龄组之间染色体畸变的关系经统计学处理,无显著性意义,但分别与对照组比较,除1～5年工龄组外,差异都较显著(P<0.05)。受照组的淋巴细胞微核率虽略高于对照组,但无统计学意义。姐妹染色单体交换频率,淋巴细胞转化率均在正常范围内。

The cytogenetics effect on 140 workers ever exposed to radiation in a uranium mine 10 years ago was investigated. As a result, the chromosomal aberration frepuencies in radioactiveo wrkers were obviously higher than controlers (P<0.05). It demonstrated that the effects of internal and external radiation exporsure could be shown, although the repair from radiation damage lasted for 10 years. There were nc significance statistic difference in chromosomal aberration among two Working category groups of 1-5, 6-10 and > 10 working-years.But comparing with control group separately, there were significances (P<0.05) cxcept 1-5 working-years group, mainly in chromosomal from aberrations. The frequencies of lymphocyte micronucleus of radiation exposed groups was higher than control group, but nostatistic meaning exist. The frepuencies of SCE and lymphocyte transformation was in normal range. Extraordinary changes were not observed.