奇奥心血丹滴丸对血小板聚集功能的影响

Effect of Qi-ao xinxuedan pellet on platelet aggregation of rabbit

目的 观察奇奥心血丹滴丸对家兔血小板聚集功能的影响。方法 采用比浊法测定体内给奇奥心血丹滴丸后对ADP诱导的血小板聚集性的影响。结果 奇奥心血丹滴丸 5 0mg/kg ,10 0mg/kg给药后 1h ,2h均能明显抑制ADP诱导的血小板聚集 ,其抑制率为 4 5 % ,4 8%和 2 4 % ,4 8%。

Objective To observe the effect of Qi ao Xinxuedan pellet on platelet aggregation of rabbit. Methods Qi ao Xinxuedan pellet was administrated in vitro. Its effect on ADP induced platelet aggregation was detected by turbid metric assay. Results Qi ao Xinxuedan pellet (50mg/kg, 100mg/kg) can significantly inhibit the platelet aggregation induced by ADP after administrated one and two hours. The inhibitory rates of each dosage are 45%,48% and 24%,48% respectively. Conclusions It showed that Qi ao Xinxuedan pellet can significantly inhibit platelet aggregation induced by ADP.