生脉注射液防治放射性肺损伤96例疗效分析

Clinical analysis on Shengmai Injection in treating radiation pneumonia and pulmonary fibrosis

目的 观察生脉注射液对于放射治疗后放射性肺炎和肺纤维化的防治效果。方法96例胸部肿瘤患者随机分为治疗组和对照组各 4 8例 ,所有病例均接受根治性放疗 ,治疗组放疗同时应用生脉注射液 4 0～ 6 0ml加入 5 %葡萄糖注射液中静脉点滴。结果 治疗组放射性肺炎和肺纤维化发生率分别是 18 8%和 16 7% ;对照组的发生率分别为 37 5 %和 35 4 % ,两组比较 ,差异有显著性 (P <0 0 5 )。结论 生脉注射液能够降低放射性肺损伤的发生率。

Objective To study the effect of Shengmai Injection in treating radiation pneumonia and pulmonary fibrosis in the course of radiotherapy. Methods Altogether 96 cases were randomly and equally alloca |ted into a treatment group and a control group,48 cases each,All patients were treated with radical radiotherapy.The initial radiotherapy was using 10 MV X-rays at conventionally fractionated dose of 60-70 Gy.Patients of the control group were given conventional radiotherapy,and those of the treatment group were given both conventional radiotherapy and Shengmai Injection 40-60 ml by iv drip for 3-5 courses,10 days for each course. Results In the treatment group,the incidences of radiation pneumonia and pulmonary fibrosis were 18.8%,16.7%,respectively,whereas in the control group they were 37.5% and 35.4%,respectively.There were significant differences between the two groups ( P <0.05). Conclusion Shengmai Injection can decrease the incidences of radiation pneumonia and pulmonary fibrosis. ;