摘要
医用微型玻璃电极采用固体可逆接触式结构 ,直径 2mm ,长约 7~ 8mm。电极用于测定人体胃液pH值与电位差 ,可诊断胃病与早期发现胃癌。研究了微型玻璃电极敏感玻璃膜的成分与性质 ,在Li2 OLa2 O3SiO2 系统中加入摩尔分数为 2 %的Ta2 O5可提高敏感玻璃的耐水性与电导率。电极在 pH值为 1~ 9范围内具有良好的Nernst响应性 ,而且重现性和稳定性均比较好。电极的酸误差较小 ,电势随时间的漂移率约为 1.5mV/h。对 2 5只大白鼠胃液的 pH值和电位差进行测定 ,测得大白鼠胃液的pH值范围为 2~ 5。与PB 2 0型SartoriusAG酸度计所测的pH值相比较 ,得知此种电极的平均偏差较小 ,约为± 0 .2。人体正常胃液酸度范围的pH值为 2~ 3 ,由此判断电极用于人体胃液的测定是可能的。
The structure of medical micro glass electrodes is reversible solid contact with the diameter of 2 mm and length of 7-8 mm. Such electrodes are used for determining the pH value and potential difference in mortal stomach juice, so that gastropathy and stomach pre-cancer can be early detected. The composition and properties of the sensitive glass film for the electrodes are studied. The water resistance and conductivity would be improved by adding 2% (in mole) Ta_2O_5 to the glass system Li_2OLa_2O_3SiO_2. A better Nernst response , stability, and reproducibility of the glass electrodes exist in the range of pH=1-9. There is a little acid error in this kind of electrode and the drift mobility of the potential difference with time is about (1.5 mV/h). The pH value and potential difference surveyed for stomach juice of 25 pieces of white rats by such electrodes is within 2-5. As compared with the measurement of pH values by PB20 Sartorius AG acidimeter, the statistical figures show that the average deviation of such electrodes is slight, approximate±0.2. The pH range of mortal stomach juice is pH=2-3 at normal status. It can be concluded from this result that it is possible to utilize for the detection of mortal stomach juice by this kind of electrodes.
出处
《硅酸盐学报》
EI
CAS
CSCD
北大核心
2004年第3期299-305,共7页
Journal of The Chinese Ceramic Society
基金
国家外国专家局 (WJ2 0 0 2 0 73 )
辽宁科委 (982 180 0 2 )资助项目
关键词
微型玻璃电极
固体接触式
胃液
大白鼠
PH值
电位差
micro glass electrodes
solid contact
stomach juice
white rat
pH value
potential difference