行为问题儿童听觉事件相关电位P300对照研究

The Auditory Event-related Potential P300 in Children with Behavior Problems

目的 :探讨行为问题儿童听觉事件相关电位P3 0 0特点。方法 :用Achenbach儿童行为问卷(CBCL)和中国联合型瑞文测验 (CRT -C2 )筛选行为问题儿童 ,并按同性别、同年龄进行 1:2配对 ;采用odd模式测试听觉事件相关电位。结果 :①问题组儿童的P3 0 0各项指标与对照组儿童无显著差异 ;②混合问题组P3 0 0潜伏期较单一问题组延迟 (P <0 0 5 ) ,Pz点P3 0 0的基线波幅混合问题组与单一问题组的差异接近有统计学意义。③行为问题儿童Pz点P3 0 0基线波幅与行为问卷总分呈显著负相关 (P <0 0 5 )。结论 :行为问题较为严重的儿童可能有认知功能损害。

Objective:To explore auditory event-related P300 in children with behavior problems. Methods: 40 children with behavior problems were screened out from a ample of pupils by CBCL and CRT-C 2. The control group was selected from the others matched by age and gender, the rate of case/control was 1:2. The study and control group were assessed by auditory event-related P300 elicited by pure tone stimuli using the oddball paradigm.Results:(1) There was no significant difference in P300 between study and control groups; (2) The P300 latency of mixed problem group were significantly longer than those of controls. (3) The P300 amplitude were significantly negatively correlated with the CBCL score.Conclusion:It is suggested cognitive function deficit of severe behavior problem children.