自身免疫性溶血性贫血的微柱凝集技术诊断应用

Clinical application of column agglutination technique in diagnosing autoimmune hemolytic anemia

目的 探讨微柱凝集体技术在诊断自身免疫性溶血性贫血 (AIHA)中的应用。方法 采用BioVue系统微柱凝集技术对 2 6例AIHA患者进行检测 ,同时用传统的试管法抗人球蛋白试验作比较。结果 统计学上两种方法对AIHA检出率无显著性差别 ,但微柱凝集技术能检出试管法所不能检出的阴性血样 ,比试管法检测凝集强度高 1 + ～ 2 + 。结论 BioVue系统微柱凝集技术能快速准确检测出AIHA ,具有更高的灵敏度 ,是直观可靠的方法。

Objective To discuss the application of columm agglutination technique (CAT)in diagnosing autoimmune hemolytic anemia (AIHA).Methods Twenty-six patients with AIHA were detected by two methods, BioVue System CAT and traditional tube agglutination technique (TAT).Results The results of detecting rate were showed not significant difference betwecen CAT and TAT.The agglutinate intention of CAT was higher 1 +～2 + than that of TAT,and CAT could increase positive rates from the negative blood samples tested by TAT. Conelusion BioVue System CAT is a rapid, reliable, sensitive method for the diagnosis of AIHA.