嗜铬细胞瘤45例临床分析

Clinical Analysis of 45 Cases of Pheochromocytoma

本文对45例嗜铬细胞瘤作了回顾性分析。全部病例均经生化或病理确诊。肿瘤位于肾上腺髓质31例,交感神经链10例,膀胱内4例。其中良性肿瘤41例,恶性肿瘤4例。临床表现以高血压为主要症状的有37例,8例无高血压为寂静型;膀胱内嗜铬细胞瘤均有肉眼血尿。测定24小时尿儿茶酚胺和VMA排出量之间有一致性,且均与血压改变呈良好正相关。定位检查以腹部CT检出率最高(92％),B超次之(82％),腹膜后充气造影检出率仅为3/4(75％)。41例行手术治疗,近期疗效及远期疗效(分别为87.5％,80％)均较乐观。

A retrospective analysis of clinical data of 45 cases of pheochromcytoma was presented. The diagnosis was confirmed by biochemical measurement or pathobiological examination. The tumours were located in adrenal medullae in 31 cases, in extre-adrenal sympathetic chain in 10cases and in urinary bladder in 4. Tumours were benign in 41 cases and malignant in 4 cases, 8 cases were normotensive, while the others were predominantly hypertensive. Patients with bladder pheochromocytoma all showed haematuria. The elevation of urinary catecholamine was consistent with that of VMA in generia. A positive correlation was found between blood picture and urinary biochemical findings. The detection rate of CT scanning (92%) was higher than that of echography (82%) or retroperioneal pneumography (75%). 41 patients had been operated on, with a short-term curative (effect of 87.5% and a long-term follow-up care rate of 80%.