摘要
以 5 芳基 1,3 环基环己二酮为原料合成了 8个未见报道的吖啶酮衍生物 ,其结构均经元素分析 ,IR和1HNMR光谱确证。其中 3 呋喃基 6 ,7 亚甲二氧基 9 甲基 1( 2H ,4H)
3-Aryl-6,7-methylenedioxy-9-methyl-1(2H,4H)-acridones and acridinols were synthesized from 5-aryl-1,3-cyclohexandione. The structures of the products were characterized by elemental analysis, IR and 1H NMR spectra. The preliminary parmacodynamic experiments show that 3-furyl-6,7-methylenedioxy-9-methyl-(2H,4H)-acridinol possesses a inhibition effect on the growth of cancer cell.
出处
《合成化学》
CAS
CSCD
2004年第3期297-299,302,共4页
Chinese Journal of Synthetic Chemistry
关键词
吖啶酮衍生物
环己二酮
肿瘤细胞
抑制
合成
acridone derivatives
cyclohexanedione
pharmadynamic activity
synthesis