纤维支气管镜介入治疗肺脓肿56例临床分析

Interventional fiberbronchoscope in treatment for lung abscess: clinical analysis of 56 cases

目的 评价纤维支气管镜 (纤支镜 )介入联合常规法治疗肺脓肿的效果。方法 对 10 8例肺脓肿患者随机分为两组 ,治疗组 5 6例经纤支镜局部冲洗和局部注药联合内科常规治疗 ;对照组 5 2例予单纯内科常规治疗。结果 治疗组治愈 5 0例 ,好转 5例 ,无效 1例 ;对照组治愈 3 7例 ,好转 8例 ,无效 5例 ,死亡 2例 ,两组治愈率比较差异有高度显著性(χ2 =5 .65 9,P <0 .0 1)。治疗组在体温恢复正常、咳痰消失、咳嗽消失以及住院时间较对照组明显缩短 (P均 <0 .0 1)。结论 经纤支镜介入联合内科常规法治疗肺脓肿 ,能显著提高疗效 ,值得临床推广应用。

Objective To assay the efficacy of interventional fiberbronscope combined with traditional internal therapy in treatment of lung abscess. Methods 108 patients with lung abscess were allocated to two groups (a therapeutic group and a control group). 56 patients of the therapeutic group received fiberbronchoscope for local irrigation and drugs infusion combined with internal traditional treatment. 52 patients of the control group were given only internal traditional treatment. Results In the therapeutic group: healing 50 cases, good remission 5 cases, ineffectiveness 1 case; in the control group: healing 37 cases, good remission 8 cases, ineffectiveness 5 cases, death 2 cases. In comparison to the two groups, there was significantly statistical difference in healing rate (χ2=5.659, P<0.01). Temperature recovery, cough and expectoration disappearance and the hospitalized time in the therapeutic group shortened more obviously than those in the control group (all the P<0.01). Conclusion Fiberbronchoscope combined with internal tradtional therapy in treatment of lung abscess can improve the efficacy and be of value in clinical recomendation.