同种异体心肺联合移植1例

Heart-lung homoplastic transplantation:a report of one case

目的 报告 1例同种异体心肺联合移植术病例。方法 2 0 0 3年 7月 1例先天性心脏病、房间隔缺损合并Eisenmenger综合征女病人在全麻、中低温、全心肺转流下进行同种异体心肺联合移植术。结果 手术顺利 ,心脏自动复跳 ,血流动力学平稳。无出血、感染和急性排异反应 ,术后 1h清醒 ,36h拔除气管插管。第 3d下床活动。术后 30d病人一般情况良好 ,各项生命指征正常 ,可在隔离病房内自由活动 ,术后 5 0d转普通病房。现已健康生存半年余 ,病人状况良好。结论 选择合适的供、受体 ,加强心肺保存 ,以及重视围术期处理 ,同种异体心肺联合移植可以挽救终末期心肺疾患病人的生命。

Objective: To report a case of heart-lung transplantation was performed in our hospital for rescue a patient suffering from congenital heart disease (ASD) with Eisenmenger's syndrome and advancing cardiac failure in July, 2003. Methods: Heart-lung homoplastic transplantation was performed under general anesthesia, moderate hypothermia and complete cardiopulmonary bypass. Results: The operation was successful. The heart rebeated automatically. Hemadynamics was stable. The patient became conscious 60 min postoperatively. The extubation was done 36 hours after operation. There were no hemorrhage, graft rejection, and infectious complications. Up to now, the patient has been living for 120 days. Conclusion: Choice of appropriate donor, emphasizing preservation techniques, and perioperation treatment may be lifesaving.