双核素心肌灌注显像对存活心肌判断

Comparison of single-isotope imaging with dualisotope myocardial tomography for evaluating viable myocardium in patients with post-myocardial infarction

目的 :观察二硝酸异山梨醇酯 (isoket)介入后铊 2 0 1(2 0 1TI)和99mTc 甲氧基异丁基异腈 (MIBI)双核素心肌断层显像检测梗死后存活心肌的敏感性及两种核素间显像结果的一致性。方法 :将 4 0例陈旧性心肌梗死(OMI)患者 ,分为A(12例 )、B(16例 )及C(12例 )三组 ,A、B组分别进行isoket介入后2 0 1TI和99mTc MIBI单核素显像 ,C组进行isoket介入后2 0 1TI及99mTc MIBI双核素心肌显像。结果 :A组摄取2 0 1TI后出现不同程度的灌注异常节段共 6 5个 ,平均得分为 9.7± 1.2。B组摄取99mTc MIBI后出现不同程度的灌注异常节段共 87个 ,平均得分 10 .8± 1.6。C组以不同核素能窗双核素显像后结果2 0 1TI心肌显像检出灌注异常节段共 4 2个 ,平均得分 5 .8± 0 .6 ;99mTc MIBI心肌显像检出灌注异常节段共 4 8个 ,平均得分 6 .1± 0 .8。A组与B及C组两种结果比较 ,均P >0 .0 5。结论 :两种核素对梗死后心肌存活力的评估一致性良好 ;双核素心肌断层显像对梗死后心肌存活力的评估与单核素心肌断层显像是一致的 。

Objective:To evaluate the consistent rate and sensitivity between single-Isotope and duaisotope myocardial tomography in Isoket-infusion 201TI and 99mTc-MIBI in detecting viable myocardium of old myocardial infarction (OMI).Method:Forty patients with OMI were divided into three groups (A,B,C). Groups A and B underwent Isoket-infusion 201TI and Isoket-infusion 99mTc-MIBI myocardial imaging respectively. Groups C were undergone Isoket-infusion 201TI and 99mTc-MIBI dualisotope myocardial imaging.Result:Groups A 12 patient ,65 radioactive segments of 201TI myocardial imaging were abnormal. The mean scores were 9.7± 1.2. Grups B 16 cases,the abnormal radioactive segments were 87 in Isoket-infusion 99mTc-MIBI myocardial imaging. The mean scores were 10.8± 1.6. Groups C 12 patients, in dualisotope myocardial imaging, 42 segments of 201TI myocardial imaging were abnormal. The mean scores were 5.8± 0.6, 48 segments of 99mTc-MIBI myocardial imaging were abnormal .The mean scores were 6.1± 0.8. There was no significant different between two methods for assessing viable myocardium P> 0.05.Conclusion:There is a good concordance between 201TI and 99mTc-MIBI imaging. Dualisotope imaging is identical with single-isotope myocardial imaging in detecting viable myocardium of OMI.