电热隔药贴灸对老年前期大鼠大脑皮质单胺类神经递质含量的影响

Effects of electric-heat medicine-separated moxibustion on monoamine neurotransmitters in the cerebral cortex of rats in pre-senile period

目的 :探讨“神阙”延缓衰老的作用机理。方法 :取 18～ 2 0月龄老年前期SD大鼠随机分组治疗 ,采用荧光比色法测定单胺类神经递质。结果 :电热隔药贴灸“神阙”穴能显著提高老年前期大鼠大脑皮质单胺类神经递质的含量 ,与老年前期空白组比较差异具有显著性意义 ,与传统隔药灸组比较差异无显著性意义。结论 :电热隔药灸“神阙”穴能够对老年前期大鼠大脑皮质单胺类神经递质含量的增龄性改变产生良性影响 ,并与传统隔药灸法的作用相似。

Objective To explore the action mechanism of “Shenque” (CV 8) in anti-aging. Methods SD rats aged 18～20 months were randomly grouped, and levels of monoamine neurotransmitters were determined with fluorimetric analysis. Results Electric-heat medicine-separated moxibustion at “Shenque” (CV 8) could significantly increase levels of monoamine neurotransmitters in the cerebral cortex of the rat in pre-senile period, with significant differences as compared with those in the control group, but with no significant differences as compared with the traditional medicine-separated moxibustion group. Conclusion Electric-heat medicine-separated at “Shenque” (CV 8) has benign effect on the age-increased changes of monoamine neurotransmitter levels in the cerebral cortex of rat in pre-senile period which is similar to that of traditional medicine-separated moxibustion.