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表皮干细胞表面标志物的研究进展 被引量：4

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摘要 表皮干细胞具有高度自我更新能力及终末分化低的特性 ,从而可维持表皮的自我更新和完整性。目前对表皮干细胞表面标志物的研究已取得了一定的进展 ,但仍然缺乏具有特异性的表面标志物。就国内外对表皮干细胞表面标志物在整合素 ,角蛋白 ,基因物质P6 3,CD71,连接蛋白 4 3,C8/ 14 4B和CD34等方面的研究进展作一综述。
作者 陈晓东 利天增 谢举临
机构地区 中山大学附属第一医院烧伤科
出处 《国外医学（生理病理科学与临床分册）》 2004年第2期202-204,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
关键词 表皮干细胞 表面标志物 整合素
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献15

  • 1Brouard M,Barrandon Y.Controlling skin morphogenesis:hope and despai [ J ].Curr Opin Biotechnol,2003,14 (5): 520 -525.
  • 2Kaur P,Li A.Adhesive properties of human basal epidermal cells:an annlysis of keratinocyte stem cell,tr-ansit amplifying cells,and postmitotic differentiating cells [ J ].J Invest Dermatol,2000,114(3):413-420.
  • 3Li A,Simmons PJ,Kaur P.Indentification and isolation of candidate human keratinocyte stem cells on cell surface phenotype [ J ].Proc Natl Acad Sci USA,1998,95:3902-3907.
  • 4Lyle S,Christofidou SM,Liu Y,et al.Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype[ J ].J Investig Dermatol Symp Proc,1999 ,4 (3) 296-301.
  • 5谢举临,利天增,祁少海,卞辉宁,成建定,徐盈斌,梁惠珍.正常人皮肤表皮干细胞定位特征对修复皮肤创伤的意义[J].中国临床康复,2003,7(4):570-571. 被引量：22
  • 6Reis-Filho JS,Torio B.p63 expression in normal skin and usual cutaneous carcinomas[ J ].Journal of Cutaneous Pathology,2002,29(9)517-523.
  • 7Little NA,Jochemsen AG.p63 [ J ].Inter J Biochem Cell Biol,2002,34: 6 -9.
  • 8Pellegrini G,Dellambra E,Golisano O,et al.p63 identifies keratinocyte stem cells[J].PNAS,2001,18(6):3156-3161.
  • 9De Laurenzi V,Rossi A,Terrinoni A,et al.p63 and p73 Transactivate Differentiation Gene Promoters in Human Keratinocytes [ J ].Biochem Biophy Res Commun ,2000,273 (1):342-346.
  • 10Lee H,Kimelman D.A dominant negative form of P63 is required for epidermal proliferation in zebrafish [ J].Dev Cell,2002,2 (5):607-616.

二级参考文献10

  • 1[1]Slack .JM. Stem Cells in Epithelial Tissues. Scierice 2000; 287:1431 -3
  • 2[2]Collins AT. Habib FK, Maitland NJ, et al. Identification and isolation of human prostate epithclial stem cells based on (alpha)2 (beta)1-integrin expression. J Cell Sci 2001; 114:3865 -72
  • 3[3]Lavker RM, Miller SJ, Sun TT. Epithelial stem cells, hair follicle, and tumor formation. Recent Results Cancer Res 1993; 128:31 -43
  • 4[4]O'Shaughnessy RF, Christiano AM. Stem cells in the epidermis. Skin Pharmacol Appl Skin Physiol 2001; 14(6): 350 -7
  • 5[5]Ghazizadeh, S, Taichman, LB. Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin. EMBO 2001; 20:1215 - 22
  • 6[6]Kume H, Teramoto S, Isurugi K. In-vivo dedifferentiation of keratinocytes to epidermal stem cells. Lancst 2002; 359(9305 ): 528 -9
  • 7[7]Collins AT, Habib FK, Maitland NJ, et al. Identification and isolation of human prostats epithelial stem cells based on (alpha)2(beta)1-integrin expression. J Cell Sci2001; 114:3865 -72
  • 8[8]Jensen UB, Lowell S, Watt FM, The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view bascd on whole-mount labelling and lineage analysis. Development 1999; 126(11):2409 -18
  • 9[9]Dunnwald M. TomanekA, Alexandrunas D, et al. Isolating a pure population of epidermal stem cells for use in tissue engineering. Exp Dermatol 200i; 10(1):45 - 54
  • 10[10]Watt FM. Stem cell fate and patterning in mammalian epidermis. Curr Opin Genet Dev 2001; 11 (4): 410 -7

共引文献21

同被引文献65

引证文献4

二级引证文献27

国外医学（生理病理科学与临床分册）
2004年 第2期

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