摘要
本文回顾复习100例睾丸生殖细胞肿瘤。分析各亚型的病理形态特征。卵黄囊瘤可有肝样、卵黄囊样、宫内膜样、乃至肠样分化;疏松的空状结构、透明小球(PAS染色阳性)有助于与胚胎性癌相鉴别。免疫过氧化物酶标记,keratin和CEA对诊断有一定意义。β—HCG是绒癌和胚胎性癌中合体滋养细胞的特异性标记。精原细胞瘤也可表达异位β—HCG。
One hundred cases of testicular germ cell tumors were reviewed pathologically and imnaunohistoc hemically.It was found that yolk sac tumors would show hepatoid, yolk sac-like, endometrioid, and intestine-like features of differentiation. The presence of a pattern of loose vacuolated network and hyaline globules is very helpful in the differential diagnosis from embryonal carcinoma. Im-munoPeroxidase studies were carried out with antibodies to keratin, CEA, and β-HCG. Keratin and CEA studies were significant in the diagnosis. β-HCG app ears to be a specific marker for syncytial trophoblasts in choriocarcinoma and embryonal carcinoma.Ectopic β-HCG might be expressed in seminoma.
出处
《蚌埠医学院学报》
CAS
1992年第1期6-8,F004,共4页
Journal of Bengbu Medical College
关键词
睾丸
精原细胞瘤
卵黄囊瘤
病理
testis
seminoma
yolk sac tumor
embryonal carcinoma
chorio-carcinoma
teratoma
keratin
CEA
β-HCG