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心肌细胞再生与心肌移植修复 被引量：1

Myocardial regeneration and cell transplantation for myocardial restoration
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摘要 过去的50年间,医学界一直认为心脏是终末分化器官(postmitotic organ),不能再生心肌细胞;心肌细胞肥大是出生后心肌细胞生长的惟一形式.心肌梗死后疤痕组织形成则是心肌细胞不能再生修复的最好例证.当心肌细胞肥厚的潜力耗尽后,细胞死亡而心力衰竭发生.但近来一些研究发现,人类与哺乳类动物心脏,在正常或病理状态下,其心肌细胞均能进行分裂增殖,以维持心肌细胞数目的动态平衡或补充死亡的心肌细胞.因此,心肌细胞是终末分化细胞的概念应该重新考虑.
作者 任晓庆 王方正 浦介麟 张澍
机构地区 中国医学科学院中国协和医科大学心血管病研究所
出处 《中华心律失常学杂志》 2004年第2期125-128,共4页 Chinese Journal of Cardiac Arrhythmias
关键词 心肌细胞 再生 心肌移植 修复 细胞死亡 增殖细胞核抗原
分类号 R541 [医药卫生—心血管疾病]
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参考文献28

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同被引文献15

  • 1尹瑞兴,杨德寨,李佳荃.心肌营养素-1对心肌梗死大鼠心功能和心肌细胞凋亡的影响[J].中华心血管病杂志,2005,33(3):273-273. 被引量：9
  • 2李丽,陶辉宇,陈杰斌,邓晖,吕建华,李双杰.黄芪甲苷保护阿霉素心肌损伤的抗氧化机制研究[J].临床儿科杂志,2007,25(1):58-61. 被引量：24
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中华心律失常学杂志
2004年 第2期

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