呼吸机相关肺炎114例病原菌及药敏分析

Characteristics of pathogens and bacterial susceptibility in ventilator-associated Pneumonia:A report of 114 cases

目的 :了解呼吸机相关肺炎 (VAP)的病原菌及其药敏情况。方法 :调查我院 2 0 0 1～ 2 0 0 2年收治的 1 1 4例VAP患者的病原菌及药敏结果。结果 :VAP患者的细菌感染为革兰阴性杆菌 6 0 .6 % ,革兰阳性球菌 2 2 .8% ,真菌 1 5 .7% ,革兰阴性球菌0 .8%。其中以铜绿假单胞菌、金黄色葡萄球菌、大肠埃希菌和真菌最为多见。超广谱 β 内酰胺酶 33.3% ,耐甲氧西林金黄色葡萄球菌 30 .0 %。结论 :VAP的细菌耐药率较高 ,在治疗VAP时应重视病原菌的培养 。

Objective:To investigate the characteristics of pathogens and bacterial susceptibility in ventilator associated pneumonia(VAP).Methods:The clinical characteristics of aetiological germ and bacterial susceptibility in 114 patients with VAP who were treated in our hospital from 2001 to 2002 were reviewed.Results: Gram negative bacillus (GNB) accounted for 60.6%, Gram positive coccus (GPC) 22.8%, fungi 15.7% and Gram negative coccus (GNC) 0.8% among the cultivated aetiological bacteria.The main microorganisms were pseudomonas aeruginosa,staphylococcus aureus and Escherichia coli .Extended stectrum β lactamases accounted for 33.3% and methicillin resistant staphylococcus aureus 30.0%.Conclusions:The bacterum of VAP has high tolerance of drugs.More attention should be paid to the cultivateion of aetiological bcteria and selection of antibiotics in the treatment of VAP.