肺部感染治疗新对策及中医药治疗的优势

New strategy for treatment of respiratory infection and the predominance of traditional Chinese medicine

肺部感染是常见疾病 ,抗生素是西医临床治疗必然的选择 ,然而抗生素治疗面临耐药病原微生物的困扰。目前一些预防和治疗肺部感染的非抗生素疗法取得了长足的进展 ,如增强机体内源性抗生素肽的产生 ,使黏膜天然免疫防御能力得以提高 ;重新重视疫苗的开发和使用 ;减少病原微生物在黏膜的黏附、定植以阻断其入侵途径以及严重感染时全身炎症反应综合征的处理等。在中药药理研究中 ,发现了不少有抗微生物作用的中药 ,其既有直接的抗菌作用 ,又有调节机体免疫功能的潜能 ,具有一定的研究和开发潜力。

Respiratory infection is a common illness. Antibiotic therapy is an essential treatment in clinical practices, but it is challenged by drug-resistant pathogenic microbes. Nowadays, there are many great improvements in some novel non-antimicrobial therapies for preventing and treating respiratory infection, such as enhancing the secretion of endogenous antibiotic peptides to improve innate immune defense of mucous membrane, attaching importance to research and application of vaccine over again, reducing the adhesion and attachment of microbes to block their invasion, and treating systemic inflammatory response syndrome resulting from severe infection. In Chinese herbal pharmacological studies, we found some herbs have antimicrobial function, and furthermore, these herbs have potential effects of immunoregulation. Chinese herbs are worthy of tapping potentialities of research and exploiture.