银杏叶注射液治疗不稳定心绞痛

The clinical efficacy and safety of ginkgo biloba extract in treatment of unstable angina pectoris

目的 评价银杏叶注射液治疗不稳定心绞痛 (UAP)的临床疗效。方法 将 72例UAP病人随机分为治疗组、对照组各 36例 ,均服用抗心肌缺血基础药物 ,治疗组加用银杏叶注射液 10ml静滴 ,每天 1次 ,连用 14d。对照组口服阿司匹林 10 0mg ,每天 1次。结果 总有效率治疗组 91 6 7% ,对照组 6 9 4 4 % (P<0 0 5 ) ;治疗组全血粘度、血浆粘度、全血还原粘度、血小板聚集率均显著降低 (P <0 0 1) ,明显低于对照组(P <0 0 5 )。结论 在常规治疗的基础上联合银杏叶注射液治疗不稳定心绞痛效果显著 ,不良反应少。

Objective To study the clinical efficacy and safety of ginkgo biloba extract in treatment of unstable angina pectoris.Methods 72 cases of unstable angina pectoris were randomly allocated into control group(n=36,recieved aspirin 100mg daily) and treatment group(n=36,recived ginkgo biloba extract 10ml put into 5% GS 250ml,for 2 weeks).Basic antimyocardial ischemia drugs were taken by both groups at the same time.Results The efficacy rate in treatment group was 91.67%;but in control group it was only 69.44%,the difference was significant(P<0.05).Total blood viscosity,plasma viscosity,total blood recovery viscosity and platelet aggregation rate in treatment group were significantly decreased(P<0.01).Conclusion Ginkgo biloba extract combined with normal traetment is an effective and safe agent for treatment of unstable angina pectoris.